Nine new norlabdane diterpenoids from the leaves of Austroeupatorium inulifolium

Yoshinori Saito; Sachie Matsuo; Suyatno Sutoyo; Motoo Tori

doi:10.1002/hlca.201000207

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Nine new norlabdane diterpenoids from the leaves of Austroeupatorium inulifolium

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Yoshinori Saito, Sachie Matsuo, Suyatno Sutoyo, Motoo Tori

2011 Helvetica Chimica Acta Vol. 94 Issue 2 Article Cited by 13 SDG 17SDG 14SDG 3SDG 12

Abstract

Nine new norlabdane diterpenoids were isolated from the leaves of Austroeupatorium inulifolium collected in Indonesia. All of them have an acyl-furan unit connected to C(11), and oxygenated functions at C(2) and C(3). The structure elucidations and the assignment of the absolute configurations of the isolated natural products were carried out by extensive spectroscopic analysis and the extended Mosher method, as well as chemical correlations. Antimicrobial activities and cytotoxicity against HL-60 cells were determined using bioassays. © 2011 Verlag Helvetica Chimica Acta AG.

Affiliations

Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima, 770-8514, Yamashiro-cho, Japan; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Surabaya State University, Jl. Ketintang Surabaya, Indonesia

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