Mulyadi Tanjung, Fida Rachmadiarti, Anindita Prameswari, Villa Ultha Wustha Agyani, Ratih Dewi Saputri, Tjitjik Srie Tjahjandarie, Yana Maolana Syah
Two new isoprenylated benzofuran 3-ones, airlanggin A (1) and B (2) along with two known xanthones, ananixanthone (3) and trapezifolixanthone (4) were isolated from the stem bark of Calophyllum soulattri. Structures of all the compounds were elucidated using extensive spectroscopic methods, including UV, IR, HRESIMS, 1D and 2D NMR. Compounds 1–4 were evaluated for their cytotoxicity against P-388 cells, showing that compound 3 was the most active with IC50 0.68 μg/mL and compound 1 showed moderate activity with IC50 5.80 μg/mL. © 2017 Informa UK Limited, trading as Taylor & Francis Group.
Faculty of Science and Technology, Department of Chemistry, Natural Products Chemistry Research Group, Organic Chemistry Division, Universitas Airlangga, Surabaya, Indonesia; Faculty of Science, Department of Biology, Universitas Negeri Surabaya, Surabaya, Indonesia; Natural Products Chemistry Research Group, Organic Chemistry Division, ITB, Bandung, Indonesia
