R. Agustini, I.G.M. Sanjaya, A. Sabarudin, A. Widodo
The number of people with type 2 DM continues to increase. This study aims to study the potential of Yeast Hydrolysate Enzymatic (YHE) as anti-type 2 DM. Yeast as a raw material for YHE is known to contain chromium which plays a role in reducing blood glucose levels. The white, red and black rice flour is used as yeast growth. This study also tested the potential of rice flour and yeast as a comparison.YHE in this study was used as an experimental animal feed for mice. YHE is determined the chemical content include: water, chromium (III) and (VI), protein, amino acids, starch, and crude fiber content. The parameters measured were glucose levels and mice body weight. Blood glucose levels of experimental animals affected by type 2 DM before and after YHE consumption for all treatments decreased. To find out the potential of YHE as anti-type 2, histology of liver and kidney tissue was also observed, as well as studies by chemical computation. The best treatment for YHE as anti-type 2 DM in this study, which was investigated from the reduction in glucose levels and body weight, was YHE-red rice (YHE-RR) feed. YHE's potential as an anti-type 2 DM was proved by histology of liver and kidney tissue. YHE's potential as an anti-type 2 DM is also proved by histology of liver and kidney tissue whereas the role of chromium in reducing glucose is supported by the results of the chemical computation. The result of this study shows that YHE from baker’s yeast fermented in several rice flour medium can be used as anti-type 2 DM. © RASĀYAN. All rights reserved.
Department of Chemistry, Surabaya State University, Surabaya, 60231, Indonesia; Department of Chemistry, Brawijaya University, Malang, 65145, Indonesia; Department of Mathematic, Brawijaya University, Malang, 65145, Indonesia
