Mulyadi Tanjung, Tjitjik Srie Tjahjandarie, Shola Mardhiyyah, Ghinsha Zakatina Rahman, Muhammad Fajar Aldin, Ratih Dewi Saputri, Norizan Ahmat
Three isoprenylated flavanones were isolated from the leaves of Flemingia lineata (L.) Aiton. Among them are two new flavanones, flemilineatins A and B (1-2), along with 6-isoprenyl eridioctyol (3). Their structures were determined using HRESIMS data and NMR spectra. Flavanones 1-3 were assayed in the HeLa cancer cells. Compound 1 showed moderate activity with an IC50 value of 11.2 µM. © 2022, Korean Society of Pharmacognosy. All rights reserved.
Natural Products Chemistry Research Group, Organic Chemistry Division, Department of Chemistry, Faculty of Science and Technology, Universitas Airlangga, Surabaya, 60115, Indonesia; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Negeri Surabaya, Surabaya, 60231, Indonesia; Faculty of Applied Sciences, Universiti Teknologi MARA, Selangor, Shah Alam, 40450, Malaysia
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