Serum dehydroepiandrosterone (Dhea) concentration after aquarobic training in premenopausal women with obesity

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Siti Baitul Mukarromah, Taufik Hidayah, Sri Sumartiningsih, Mohammad Arif Ali, Abdul Azis Hakim, Ronny Lesmana, Nguyen Tra Giang

2021 Journal of Physical Education and Sport Vol. 21 Article Cited by 6 Quartile

Abstract

Background: The prevalence of obesity which is characterized by an increase in excess body weight occurs worldwide, including Indonesia, with 8.1% of obese men and 13.5% of obese women. Dehydroepiandrosterone (DHEA) is a precursor to the hormone DHEA, a sex steroid hormone produced by the adrenal cortex, and its concentration decreases with age have not precisely been decide in obese people regulation by aquarobics training (recommended sport type or obese people). This research aims to investigate the Dehydroepiandrosterone (DHEA) concentration of obese people based on BMI, examine their relationship with obesity-related parameters and how it can be modulated by aquarobic training in premenopausal women with obesity. Methods: The experimental laboratory research design using the design of The Randomized Pretest-Posttest Control Group Design, conducted on 20 healty volunteers women obese from 45 – 55 years old, was divided into 2 groups where group 1 (n=10) aquarobics training intensity 70-85% HRmax for 8 weeks and control group (n=10). Measurement of the Dehydroepiandrosterone (DHEA) concentration Using enzyme-linked immunosorbent assay (ELISA) methods, measuring other factors like Low Density Lipoprotein and cholesterol level before and after treatment. Result: Aquarobic training group pre-test BMI 31.32+0.97kg/m2, DHEA 66.92+22.65 nmol/l and cortisol levels 9.67+3.37 nmol/l; Post-test BMI 30.24+1.18 kg/m2, DHEA 82.25+21.52 nmol/l and cortisol levels 7.60+3,11 nmol/l (p<0.05). control group pre-test BMI 32.48+1.56kg/m2, DHEA 63.83+24.09 nmol/l and cortisol levels 7.70+1.65 nmol/l; Post-test BMI 33.18+1.56kg/m2, DHEA 65.53+22.09 nmol/l and cortisol levels 8.23+1.44 nmol/l (p>0.05). Conclusion: it was observed that aquarobics training intensity 70-85% HRmax for 8 weeks significantly increased DHEA concentration and decreased cortisol levels, DHEA may play an important role in obesity and can be potentially modulated by aquarobic training. © JPES.

Affiliations

Department of Sport Science, Faculty of Sport Science, Universitas Negeri Semarang, Semarang, Indonesia; Department of Sport Science, Faculty of Sport Science, Universitas Negeri Surabaya, Surabaya, Indonesia; Department of Anatomy, Physiology, and Biology of Cell, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia; Faculty of Sport Science and Technology, Bangkokthonburi University, Thailand