Response of TNF-α Levels and Blood Glucose Levels after Acute High-Intensity Intermittent Exercise in Overweight Women; [Respuesta de los niveles de TNF-α y niveles de glucosa en sangre después del ejercicio agudo intermitente de alta intensidad en mujeres con sobrepeso]

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Angelia Indra Devi, Purwo Sri Rejeki, Raden Argarini, Nur Shakila, Yosnengsih Yosnengsih, Siti Badriyah Zahrotul Ilmi, Aldi Karimullah, Novadri Ayubi, Lilik Herawati

2023 Retos Vol. 48 Article Cited by 14 Quartile

Abstract

Sedentary behavior is a lifestyle that plays a role in the pathophysiology of obesity or overweight. TNF-α is an inflammatory cytokine that can affect glucose metabolism and can trigger insulin resistance. Acute HIIE is exercise with alternating periods of high-intensity exercise and periods of active recovery. The purpose of this study was to examine the changes of TNF-α and blood glucose levels after acute HIIE in overweight women. Subjects were overweight women, divided into 2 groups (K1=control group and K2=experimental group; n=7) with a body mass index between 23.00 and up to 24.99 kg/m2. The acute protocol of HIIE with ergocycle consisted of a 3-minute warm-up (starting at 40 rpm), core exercise for 60 s at 80%-90% of HRmax, interspersed with 60 s of active recovery (40 rpm), and cool-down for 2 minutes. The pre-test was performed before treatment and the post-test was performed 60 minutes after treatment. Serum TNF-α levels were measured by the human enzyme-linked immunosorbent assay (ELISA) method. Blood glucose changing levels were taken by finger prick. The result showed that the change of TNF-α (the difference of pre and post) was a significant decrease in the K1 and K2 group (p<0.05), and the K2 group less decrease compared to K1. Blood glucose was significant (p<0.05). This study can be concluded that the TNF-α level is unchanged and the blood glucose levels is increase in overweight women with sedentary behavior performing acute HIIE. © Federación Española de Asociaciones de Docentes de Educación Física (FEADEF).

Affiliations

Universitas Airlangga, Indonesia; National University of Malaysia, Malaysia; Universitas Negeri Surabaya, Indonesia