Sendy Mohamad Anugrah, Nining Widyah Kusnanik, Endang Sri Wahjuni, Novadri Ayubi, Rizki Mulyawan
Heavy and excessive physical activity can result in injury or muscle damage in ordinary people and athletes, hence diminishing their physical ability during training and competition. It has been established that royal jelly possesses antioxidant and anti-inflammatory effects and enhances athletic performance. This study aims to go through the published research on royal jelly to find evidence that it improves performance and reduces inflammation after muscle injury. The method employed is Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). The databases included Pubmed/MEDLINE, Scopus, Web of Science, and Embase. The ten papers' objectives, topic suitability, sample size, research technique, funding, and commentary were assessed. This research review reveals that royal jelly reduces the subjective sense of muscle pain intensity; reduces muscle damage via a decrease in creatine kinase (CK); improves muscle function; modulates pro-inflammatory cytokines such as TNF-a, IL-6, and IL-8; and has an antioxidant impact. Administration of royal jelly at doses ranging from 300 to 3000 mg/day before, during, and 72 hours after exercise enhances performance by lowering EIMD and regulating physical activity-induced inflammation. Conclusion Royal jelly enhances performance and the inflammatory response to muscle injury. Royal Jelly can be used as a dietary supplement by athletes and other physically active people whose activities cause muscle injury and inflammation. © 2023 by the authors.
Universitas Negeri Surabaya, Indonesia; Faculty of Sport Science, Universitas Negeri Yogyakarta, Indonesia
