Shola Mardhiyyah, Mufidatuz Zakiyah, Erika D. Renata, Tjitjik S. Tjahjandarie, Unang Supratman, Rurini Retnowati, Ratih D. Saputri, Mulyadi Tanjung
Two xanthones, gerontoxanthone I and macluraxanthone, were isolated from the stem bark of Cratoxylum sumatranum. Their structures were determined based on UV, HRESI-MS, 1D, and 2D NMR spectral data. Compounds 1 and 2 showed high activity against T47D cells with an IC50 of 1.10 and 1.60 μg/mL. © 2023 Mardhiyyah et al.
Natural Products Chemistry Research Group, Organic Chemistry Division, Department of Chemistry, Faculty of Science and Technology, Universitas Airlangga, Surabaya, Indonesia; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor, 45363, Indonesia; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Brawijaya, Malang, 65145, Indonesia; Organic Chemistry, Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Negeri Surabaya, Surabaya, 60231, Indonesia