Wijono Wijono, Muhammad Kharis Fajar, Tutur Jatmiko, Mochamad Purnomo, Oce Wiriawan, Bayu Agung Pramono, Yetty Septiani Mustar, I. Dewa Made Aryananda Wijaya Kusuma, Mert Kurnaz, Rachman Widohardhono, Waristra Tyo Nirwansyah, Adi Pranoto
Background and Study Aim Material and Methods Results Conclusions Physical exercise is widely recognized as an effective strategy for improving health and quality of life. The purpose of this study was to analyze the effects of high-intensity and low-intensity strength training, as well as high-intensity aerobic exercise, on serum Interleukin-10 (IL-10) production. Thirty college students were recruited to undergo different training programs in each group. The study employed an experimental design with three exercise groups: high-intensity strength training (STH), low-intensity strength training (STR), and high-intensity aerobic exercise (AH). Each group included 10 participants, and serum IL-10 levels were measured before exercise and 24 hours post-exercise. To assess long-term effects, participants trained three times per week for four weeks under carefully monitored conditions. The results showed that all types of exercise significantly increased serum IL-10 levels. The AH group exhibited the highest increase, followed by the STR and STH groups. These findings align with previous studies demonstrating an increase in IL-10 following high-intensity aerobic exercise. The elevated IL-10 levels in the AH group can be attributed to improved cardiovascular capacity and the body’s inflammatory response. Strength training, despite not increasing VO2max, also led to an IL-10 increase, though the effect was smaller compared to aerobic exercise. High-intensity aerobic exercise is more effective at increasing IL-10 production compared to strength training. This study suggests combining both types of exercise to maximize immunological benefits. Such an approach can also enhance post-exercise recovery. It is important to consider the duration and recovery intervals, as these factors influence the immune response. © Wijono, Muhammad Kharis Fajar, Tutur Jatmiko, Mochamad Purnomo, Oce Wiriawan, Bayu Agung Pramono, Yetty Septiani Mustar, I Dewa Made Aryananda Wijaya Kusuma, Mert Kurnaz, Rachman Widohardhono, Waristra Tyo Nirwansyah, Adi Pranoto, 2025.
Department of Sport Coaching, Faculty of Vocational, Universitas Negeri Surabaya, Indonesia; Department of Sport Coaching Education, Faculty of Sport and Health Science, Universitas Negeri Surabaya, Indonesia; Department of Sport Science, Faculty of Sport and Health Science, Universitas Negeri Surabaya, Indonesia; Department of Sports Sciences, Haliç University, Turkey