Mohammad Budiyanto, Fasih B. Ilhami, Andika P. Wardana, Nora Ertanti, Sapti Puspitarini
The development of new composite materials derived from plant-based carbon for biomedical applications has posed a considerable challenge over the past decades. Herein, we successfully designed and synthesized ZnO/Meniran-C from Meniran-derived carbon (Meniran-C) decorated on zinc oxide for effective cancer treatment. These composites showed crystal microparticles and provided unique optical properties with high absorbance compared to pure Meniran and ZnO under an aqueous solution which has the potential for increased electron-hole. More importantly, in vitro analysis of MDA-MB-231 cells as breast cancer cells exhibited high toxicity after incubation with ZnO/Meniran-C for 24 h, in comparison with incubation with Meniran only. Hence, these composite materials provide a novel composite from bioactive compounds Meniranderived carbon with excellent anticancer therapy and offer significant potential to contribute to the development of cost-effective, environmentally friendly, and widely applicable cancer therapies for future applications. © The Authors 2025.
Department of Natural Science, Faculty of Mathematics and Natural Science, State University of Surabaya, Surabaya, Indonesia; Department of Chemistry, Faculty of Mathematics and Natural Sciences, State University of Surabaya, Surabaya, Indonesia; Stem Cell Research and Development Center, Airlangga University, Surabaya, Indonesia
