Browi Nugroho, Sari Edi Cahyaningrum
Tooth decay is caused by the activity of Streptococcus mutans bacteria. One of the efforts to prevent tooth decay is to use toothpaste that contains antibacterial compounds such as hydroxyapatite, nanosilver and clove oil. The purpose of this study is to synthesize and characterize hydroxyapatite-nanosilver-clove oil as an antibacterial agent against dental caries and describe the properties that can be felt by the five senses of humans, namely the taste, aroma, color, texture of the toothpaste produced. In this study, physical properties were tested, namely particle size using the Particle Size Analyzer instrument, dispersion, adhesive power, homogeneity and chemical properties using the Fourier- Transform Infrared instrument in the form of functional groups, pH, and antibacterial activity using the plate diffusion method. The results of the FTIR characterization showed the existence of typical functional groups OH-, CO32-, PO43-, C-H, C-O, and C=O, then the particle size produced was above 100 nm, pH according to SNI (4.5-10.5), and the dispersion test met the standard (5-7 cm). However, the adhesion is not yet ideal (1-6 seconds). Antibacterial tests showed that the formulation with 4% clove oil produced the highest inhibitory diameter (14.99 mm) against S. mutans. Organoleptic testing with 20 panelists showed that formulations with 2% clove oil were the most preferred, while 4% clove oil was less preferred. © 2025 Author(s).
Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Negeri Surabaya, Jl. Ketintang, Gayungan, East Java, Surabaya, 60231, Indonesia
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