Abdul Rohim Tualeka, Gurendro Putro, Aceng Ruyani, Susmiati Susmiati, Aris Santjaka, Aisy Rahmania, Tri Niswati Utami, Ellyza Setya Maryiantari, Dewi Rokhmah, Farhana Syahrotun Nisa S, Dimas Rahadian Aji Muhammad, Roy Januardi Irawan, Rizky Rahadian Wicaksono, Mintje Maria Nendissa, Sunardi Sunardi, Iswari Hariastuti, Nur Mukarromah, Dina Keumala Sari, Nana Dyah Siswati, Rizaldy Fathur Rachman, Velu Perumal, Suardi Zurimi, Salsabila Novianti, Juliana Jalaludin, Rachmy Rosyida, Eko Nurmianto, Ikhram Hardi Syamsuddin, Umi Salmah
The concentration of toluene in the industry has been above the threshold. This study aims to analyze the effect of toluene exposure on MDA, creatinine and BUN levels in Airlangga University Press Surabaya printing workers. This type of study is observational. The design of this study was cross sectional.The location of this research was carried out in the printing industry of Airlangga University Press Surabaya starting in October 2022 – January 2023.The sample size is a total population of 14 respondents. Research variables include respondent characteristics, toluene, bun, creatinine. Primary data collection on respondents' characteristics was conducted through interviews using questionnaires and observations. Data Analysis is used Descriptive analysis, Crosstabulation, Strong Analysis of the impact. The maximum value of the toluene concentration obtained is 3.4465 ppm and the minimum value is <0.0516 ppm. Theaverage level of Malondialdehyde (MDA) is 4.184 nmol/ml with the maximum value is 5.134 nmol/ml while the minimum value is 3.284 nmol/ml. The standard deviation for MDA levels is 0.517. Workers who had MDA levels ≥ 1.076, workers aged <37 years and ≥ 37 years had abnormal MDA levels. Workers had a maximum creatinine level value of 1.17 mg/dL and a minimum value of 0.65 mg/dL. Ror the average value of BUN levels is 35 ng / dL. The most influential toluene exposure on BUN levels was obtained Standard Coeficient (Beta) value of 0.788 then MDA levels with Standard Coeficient (Beta) value of 0.762 and finally creatinine levels showed a value of 0.586. Blood tests showed that the worker had high levels of MDA, and for creatinine levels and BUN levels in the normal category. Toluene exposure has the most effect on BUN levels, then MDA levels, and creatinine levels. © 2025 by SPC (Sami Publishing Company).
Department of Occupational Health and Safety, Public Health Faculty, Airlangga University, East Java, Surabaya, 60115, Indonesia; Center Research for Public Health and Nutrition, National Research and Innovation Agency, Indonesia; Program Studi Pendidikan Biologi, Fakultas Keguruan dan Ilmu Pendidikan, Universitas Bengkulu, Jl. WR. Supratman, Kandang Limun, Kec. Muara Bangka Hulu, Bengkulu, 38371, Indonesia; Universitas Kadiri, Indonesia; Poltekkes Kemenkes Semarang, Indonesia; Occupational Health and Safety, Health Science Faculty, Universitas Darussalam Gontor, Indonesia; Faculty of Public Health, State Islamic University of North Sumatra, Indonesia; Department of Occupational Health and Safety, Kerta Cendekia Health Polytechnic, Indonesia; Department of Health Promotion and Behavior Science, Public Health Faculty, University of Jember, Indonesia; Sekolah Vokasi, Universitas Sebelas Maret, Indonesia; Department of Food Science and Technology, Universitas Sebelas Maret, Jl. Ir Sutami 36A, Surakarta, 57126, Indonesia; Sports Science and Health Faculty, Universitas Negeri Surabaya, Indonesia; Environmental Health Study Programme, Faculty of Health Sciences, Universitas Islam Lamongan, Indonesia; Politeknik Kesehatan Kemenkes Maluku, Indonesia; Universitas Karya Persada Muna, Indonesia; Research Center for Population, The Nasional Research and Innovation Agency, Indonesia; Faculty of Health Science, Universitas Muhammadiyah of Surabaya, Indonesia; Faculty of Medicine, University of Sumatera Utara, Indonesia; Department of Chemical Engineering, Faculty of Industrial Engineering, Universitas Pembangunan Nasional “Veteran” East Java, Surabaya, Indonesia; Politeknik Kesehatan Bhakti Pertiwi Husada Cirebon, Indonesia; Jabatan Rekabentuk Perindustrian, Fakulti Rekabentuk dan Senibina, Universiti Putra Malaysia, Selangor Darul ehsan, Serdang, 43400, Indonesia; Department of Occupational Health and Safety, Airlangga University, Java East, Surabaya, 60115, Indonesia; Department of Occupational Health and Environment, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, UPM, Selangor, Serdang, 43400, Malaysia; 2Department of Occupational Health and Safety, Airlangga University, Indonesia; Department of Public Health, Faculty of Sports Science, State University of Malang, Indonesia; Department of Industrial and Systems Engineering, Institut Teknologi Sepuluh Nopember, Surabaya, Indonesia; Department of Occupational Health and Safety, Faculty of Public Health, Universitas Muslim Indonesia, Makassar, Indonesia; Faculty of Public Health, Universitas Sumatera Utara, Indonesia
